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Do you have a medical problem? Medical Knowledge, Diagnostics, Treatment and Disease Prevention.Articles by Aleksandr Kavokin, MD, PhD
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    Title: What is Cirrhosis of the Liver?
    Article:Liver neutralizes and removes poisons from your blood.
    It also makes immunological substances to fight
    infections, makes proteins for blood clotting and bile
    for uptake of fats and vitamins in your gut.
    Cirrhosis of the liver means scarring that replaces
    healthy tissue. Cirrhosis often leads to death.
    Cirrhosis also requires a lot of medical resources for
    treatment.
    Main causes of cirrhosis are chronic alcoholism and
    hepatitis C. Hepatitis B was remarkable before, but
    decreased at present time because of widespread
    vaccinations in western countries. It is still
    significant in other countries.
    Alcoholism, in fact, is only one of the causes.
    Alcoholic cirrhosis comes after several years of heavy
    drinking. Women are more vulnerable then men. Alcohol
    blocks the normal processing of proteins and fats.
    Chronic hepatitis C leads to inflammation and damage
    of liver. It is not very extensive, but chronic
    inflammation during many years leads to cirrhosis.
    Chronic hepatitis B is the most common cause of
    cirrhosis worldwide. Untreated hepatitis B also causes
    chronic inflammation that leads to cirrhosis after
    several years. Hepatitis D is caused by a special
    defective virus that infects the liver only in
    patients with hepatitis B.
    Autoimmune hepatitis is caused by the immune attack
    against own body.
    Inherited diseases, such as alpha-1 antitrypsin
    deficiency, galactosemia, and glycogen storage
    diseases also damage liver. Such inherited disease as
    hemochromatosis cause liver damage by overload with
    iron. Wilson's disease causes liver damage by overload
    with copper.
    Adverse reaction to drugs, environmental poisons, and
    special worm infection schistosomiasis may lead to
    cirrhosis.
    If bile ducts are blocked in babies inherently or in
    adults during primary biliary cirrhosis, the outcome
    is scarring and cirrhosis. Secondary biliary cirrhosis
    happens after surgery if the ducts were injured.
    Nonalcoholic steato-hepatitis (NASH) is associated
    with diabetes, protein misbalance, obesity, and
    coronary artery disease. Eventually, it may lead to
    cirrhosis too.
    Advanced heart disease with heart failure cause liver
    congestion and may cause cirrhosis


    What are Cirrhosis Symptoms?
    Peoples with cirrhosis experience:
    *Fatigue
    *Decreased appetite
    *Yellowing of the skin and eyes - Jaundice
    *Nausea
    *Weight loss
    *Belly pain
    *Edema (swelling)
    *Ascites (fluid in abdominal cavity)
    *Small spidery blood vessels on the skin
    *Easy bruising
    *Bleeding
    *Reddening of hands
    *Itching (from accumulated in the skintoxins)
    *Gallstones
    *Brain damage by non-removed toxins – Encephalopathy
    *Personality changes.

    The late stages lead to coma, and death.
    Also patient with cirrhosis do not tolerate other
    medications well. Normal liver removes drugs from the
    blood. Damaged liver causes build up of the drugs in
    the body.
    Cirrhosis slows the normal flow of blood through the
    portal vein, and increases the. This leads to varices
    (enlarged blood vessels), which burst and cause
    signifcant bleeding in esophagus.
    Cirrhosis also causes resistance to insulin and type 2
    diabetes.
    Eventually cirrhosis leads to liver cancer -
    hepatocellular carcinoma.
    Cirrhosis can also cause impotence, damage of kidneys
    and weak bones.

    Check More Information at:
    American Liver Foundation
    www.liverfoundation.org

    Symptoms check on-line
    www.rdoctor.com

    Hepatitis Foundation International
    www.hepfi.org

    Centers for Disease Control and Prevention
    www.cdc.gov

    United Network for Organ Sharing
    www.unos.org
    Author:Aleksandr Kavokin, MD, PhD
    System:Liver
    Subject:Cirrhosis
    Abstract:Main causes of cirrhosis are chronic alcoholism and
    hepatitis C.
    Website:www.kavokin.com
    Time:18:03
    Reference: 
    Reference 2: 

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